I still remember the first time I slathered mayo on chicken instead of a complicated sauce and the oven did the rest. This Mayonnaise-Parmesan Chicken is one of those reliably simple bakes: creamy, golden-topped chicken breasts that come together with pantry ingredients and little babysitting. It’s perfect for busy weeknights, picky eaters, or when you want something comfortingly familiar without a lot of fuss. If you enjoy easy, family-friendly recipes, you might also like this crockpot chicken tortilla soup recipe as another no-stress dinner option.
Why you’ll love this dish
This recipe turns two humble ingredients—mayonnaise and Parmesan—into a flavorful, slightly crisp coating that keeps chicken juicy. The mayo (or Greek yogurt) locks in moisture while the Parmesan browns and adds savory depth. It’s quick to assemble, uses common pantry spices, and yields a dinner that feels a little special without much effort.
“A weeknight lifesaver: creamy, golden, and the kids asked for seconds. Super simple cleanup too.”
What makes this ideal: minimal prep, modest grocery needs, and dependable results whether you’re feeding one person or four. It’s also forgiving—swap mayo for yogurt, add herbs, or sprinkle extra cheese and you’ll still get a winner.
Step-by-step overview
You’ll prep the chicken to an even thickness, mix a creamy Parmesan coating, spread it onto the breasts, and bake until the centers hit 165°F (74°C). Expect total hands-on time to be about 10 to 15 minutes and oven time around 35 to 45 minutes. The technique is straightforward: pound, coat, bake, rest.
What you’ll need
- 4 boneless, skinless chicken breasts
- 1 cup mayonnaise or plain Greek yogurt (see notes below)
- 1/2 cup grated Parmesan cheese
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon salt
- 1/2 teaspoon black pepper
- Optional: 1/2 teaspoon paprika or Italian seasoning
Notes on ingredients and substitutions:
- Swap mayo for plain Greek yogurt for a tangier, slightly lighter coating. Use full-fat yogurt for best texture.
- Freshly grated Parmesan melts and browns more evenly than pre-grated powder.
- For a smokier edge, add a pinch of smoked paprika in place of regular paprika.
- Make it dairy free by using vegan mayo and nutritional yeast instead of Parmesan, though the flavor and browning will be different.
Step-by-step instructions
- Preheat the oven to 375°F (190°C). Grease a 9×13-inch baking dish.
- Place a chicken breast between two sheets of plastic wrap and pound gently to an even thickness of about 3/4 inch. Repeat with remaining breasts.
- In a medium bowl, whisk the mayonnaise or yogurt with the Parmesan, garlic powder, onion powder, salt, and black pepper until smooth.
- Spread a generous layer of the mixture over the top of each chicken breast so the surface is well coated.
- Arrange the coated breasts in the prepared baking dish. Sprinkle optional paprika or Italian seasoning over them if using.
- Bake uncovered for 35 to 45 minutes, until an instant-read thermometer inserted into the thickest part registers 165°F (74°C) and juices run clear. The top should be golden.
- Remove from the oven and let the chicken rest for 5 minutes before slicing and serving.

Best ways to enjoy it
Serve this chicken sliced over simple sides to highlight the creamy Parmesan topping. Great pairings include:
- Mashed potatoes or cauliflower for a cozy plate.
- Steamed green beans, roasted asparagus, or a crisp salad to add brightness.
- Tossed pasta (buttered or with a light lemon vinaigrette) for an easy weeknight pasta-and-protein meal.
- Warm crusty bread to mop up any juices.
For a slightly elevated presentation, slice the chicken and fan it over mixed greens, then drizzle with a touch of olive oil and a squeeze of lemon. If you want another baked chicken idea with a different flavor profile, try the garlic butter baked chicken breast recipe for inspiration.
Storage and reheating tips
- Refrigeration: Cool leftovers within two hours and store in an airtight container for up to 3 to 4 days.
- Freezing: Place cooled chicken in a freezer-safe container or bag and freeze for up to 3 months. Thaw overnight in the refrigerator before reheating.
- Reheating: For best texture, reheat in a 350°F (175°C) oven until warmed through, about 15 to 20 minutes for refrigerated portions. To retain juiciness, cover loosely with foil and check that internal temperature reaches 165°F (74°C). Microwaving is quicker but can dry the chicken; use short bursts and cover to retain moisture.
- Food safety: Always reheat leftovers to 165°F (74°C) and do not refreeze fully thawed chicken without cooking it first.
Pro chef tips
- Pound to even thickness so every breast cooks in the same time and stays juicy.
- Use an instant-read thermometer to avoid overcooking; 165°F (74°C) is the safe internal temperature for chicken.
- If you want a browner top, switch the oven to broil for the last 1 to 2 minutes while watching closely. Keep the dish a few inches below the broiler and do not walk away.
- For extra texture, mix 1/4 cup panko breadcrumbs into the mayo-Parmesan mixture before spreading. Brush the top with a little melted butter to help browning.
- If meal prepping, bake the chicken fully, cool, then slice and portion with sides for easy grab-and-go lunches.
Creative twists
- Herby lemon: Add 1 tablespoon chopped fresh parsley and 1 teaspoon lemon zest to the mayo mixture for brightness.
- Spicy kick: Stir in 1/4 to 1/2 teaspoon red pepper flakes or cayenne to the coating.
- Crunch topping: Combine 1/4 cup panko with 2 tablespoons melted butter and sprinkle over the chicken before baking.
- Low carb: Serve over cauliflower rice or zoodles to keep the plate light.
- Make it dairy free: Use vegan mayo plus 2 tablespoons nutritional yeast, and increase seasoning to compensate for lost saltiness.
Common questions
Can I use Greek yogurt instead of mayonnaise?
Yes. Plain Greek yogurt is a great swap and gives a tangier, slightly lighter result. Use full-fat yogurt for best texture. If the yogurt is very watery, strain it briefly through a fine mesh to thicken.
How do I know when the chicken is done?
The safest and most reliable method is an instant-read thermometer. Insert it into the thickest part of the breast; it is done at 165°F (74°C). Juices should run clear and the top should be golden.
Can I prepare this ahead of time?
You can assemble the chicken in the baking dish, cover tightly, and refrigerate for up to 24 hours before baking. Add a few extra minutes to the bake time if the chicken goes into the oven chilled.
Will the topping get soggy if I refrigerate leftovers?
The mayo-Parmesan topping softens in the fridge but remains flavorful. To restore some crispness, reheat uncovered in a 350°F (175°C) oven or place under the broiler for a minute while watching carefully.

Mayonnaise-Parmesan Chicken
Ingredients
Method
- Preheat the oven to 375°F (190°C). Grease a 9×13-inch baking dish.
- Place a chicken breast between two sheets of plastic wrap and pound gently to an even thickness of about 3/4 inch. Repeat with remaining breasts.
- In a medium bowl, whisk the mayonnaise or yogurt with the Parmesan, garlic powder, onion powder, salt, and black pepper until smooth.
- Spread a generous layer of the mixture over the top of each chicken breast so the surface is well coated.
- Arrange the coated breasts in the prepared baking dish. Sprinkle optional paprika or Italian seasoning over them if using.
- Bake uncovered for 35 to 45 minutes, until an instant-read thermometer inserted into the thickest part registers 165°F (74°C) and juices run clear. The top should be golden.
- Remove from the oven and let the chicken rest for 5 minutes before slicing and serving.


